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CALL FOR PAPERS “Analysis and Control of Biological Networks”
05/02/2010 -

A Special Issue of Asian Journal of Control

In systems biology, one of the ultra goals is to engineer unnatural organic molecules
that function in living systems to investigate natural biological phenomena and for
a variety of applications. In control engineering, the overall aim is to synthesize
controllers which can achieve desired performance. The notion of feedback, which is
the core of control engineering, is now a central recurring theme in the design of
biological regulatory networks. In fact, feedback is so prevalent in biological
systems that it can be found at all levels of organization, from the molecular and
cellular levels, to the organism and ecological levels. It is impossible to overstate
the importance of feedback as a strategy for the maintenance and evolution of life.
Therefore, it is reasonable to expect that ideas from control theory will lead to new
understanding of the underlying biological processes, and therefore have potential
applications in system biology and synthetic biology.

The complexity of biological networks (BNs) poses many challenges for scientists and
engineers. In particular, the biological systems have apparently become dependent on
the complex infrastructure of the networks to such an extent that it is difficult to
analyse and control these networks thoroughly with our current capabilities. Therefore,
there is an urgent need to research into modelling, analysis, synchronization and control
of BNs using the available systems and control theory. Although many fundamental questions
have been addressed with the hope to understand network structures and dynamic properties,
some major problems have not been fully investigated, such as the behaviours of switching,
oscillating, stability, synchronization and chaos control for BNs, as well as their
applications in systems biology and bioinformatics.

This special issue aims to bring together the latest advances in analysis and control of
biological networks, which comprise gene regulatory networks, signal transduction

metabolite networks and intra-species or interspecies communication networks in microbial
communities. Topics of this special include, but are not limited to the following aspects:
(1) systems and control analysis of BNs; (2) Modelling of BNs; (3) dynamics analysis of
regulatory motifs; (4) robustness and fragility analysis of BNs; (5) synchronization of
BNs; (6) design of synthetic BNs, and (7) methods and algorithms for BN analysis.

Guest Editors:           
Prof. Luonan Chen
Osaka Sangyo University
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Prof. James Lam
The University of Hong Kong
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Prof. Zidong Wang
Brunel University
United Kingdom
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Important Dates:
Jan. 1,  2010         Call for Papers
June 30, 2010         Deadline for Paper Submission
Oct. 31, 2010         Completion of First Review
Feb. 28, 2011         Completion of Final Review
Sep. 30, 2011         Publication (Tentatively Vol.13, No.5)

Potential authors are strongly encouraged to upload the electronic file of their manuscript
(in PDF format) through journal website:

If you encounter any submission problem, feel free to contact Prof. Li-Chen Fu, Editor-in-Chief:
     Professor Li-Chen Fu
     Department of Electrical Engineering, EE II-524
     National Taiwan University
     Taipei 10617, Taiwan
     Tel: +886-2-3366-3558
     Fax: +886-2-2365-4267
     E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

All submission should include a title page containing the title of the paper, an abstract
and a list of keywords, authors’ full names and affiliations, complete postal and electronic
address, phone and fax numbers. The contacting author should be clearly identified. For detailed
submission guidelines, please visit


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